Wogonin suppresses stem cell-like traits of CD133 positive osteosarcoma cell via inhibiting matrix metallopeptidase-9 expression

• Main Authors: Do Luong Huynh (Author), Taeho Kwon (Author), Jiao Jiao Zhang (Author), Neelesh Sharma (Author), Meeta Gera (Author), Mrinmoy Ghosh (Author), Nameun Kim (Author), Somi Kim Cho (Author), Dong Sun Lee (Author), Yang Ho Park (Author), Dong Kee Jeong (Author)
• Format: Book
• Published: BMC, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Several efforts have been deployed to cure osteosarcoma, a high-grade malignant bone tumour in children and adolescents. However, some challenges such as drug resistance, relapse, and tumour metastasis remain owing to the existence of cancer stem cells (CSC). There is an urgent n...