Deciphering the Antibacterial Mechanisms of 5-Fluorouracil in <i>Escherichia coli</i> through Biochemical and Transcriptomic Analyses

• Main Authors: Muchen Zhang (Author), Huangwei Song (Author), Siyuan Yang (Author), Yan Zhang (Author), Yunrui Tian (Author), Yang Wang (Author), Dejun Liu (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The emergence of carbapenem-resistant Gram-negative pathogens presents a clinical challenge in infection treatment, prompting the repurposing of existing drugs as an essential strategy to address this crisis. Although the anticancer drug 5-fluorouracil (5-FU) has been recognized for its antibacteria...