SAMe, Choline, and Valproic Acid as Possible Epigenetic Drugs: Their Effects in Pregnancy with a Special Emphasis on Animal Studies

• Main Authors: Asher Ornoy (Author), Liza Weinstein-Fudim (Author), Maria Becker (Author)
• Formato: Libro
• Publicado: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

In this review, we discuss the functions and main effects on pregnancy outcomes of three agents that have the ability to induce epigenetic modifications: valproic acid (VPA), a well-known teratogen that is a histone deacetylase inhibitor; S-adenosylmethionine (SAMe), the most effective methyl donor;...