Self-Emulsifying Formulations to Increase the Oral Bioavailability of 4,6,4'-Trimethylangelicin as a Possible Treatment for Cystic Fibrosis

• Main Authors: Erica Franceschinis (Author), Marco Roverso (Author), Daniela Gabbia (Author), Sara De Martin (Author), Matteo Brusegan (Author), Christian Vaccarin (Author), Sara Bogialli (Author), Adriana Chilin (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2022-08-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

4,6,4'-trimethylangelicin (TMA) is a promising pharmacological option for the treatment of cystic fibrosis (CF) due to its triple-acting behavior toward the function of the CF transmembrane conductance regulator. It is a poorly water-soluble drug, and thus it is a candidate for developing a sel...