Kidney derived apolipoprotein M and its role in acute kidney injury

• Main Authors: Line S. Bisgaard (Author), Pernille M. Christensen (Author), Jeongah Oh (Author), Federico Torta (Author), Ernst-Martin Füchtbauer (Author), Lars Bo Nielsen (Author), Christina Christoffersen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: Apolipoprotein M (apoM) is mainly expressed in liver and in proximal tubular epithelial cells in the kidney. In plasma, apoM associates with HDL particles via a retained signal peptide and carries sphingosine-1-phosphate (S1P), a small bioactive lipid. ApoM is undetectable in urine from healthy...