Flow Patterns and Particle Residence Times in the Oral Cavity during Inhaled Drug Delivery

• Main Authors: Brenda Vara Almirall (Author), Kiao Inthavong (Author), Kimberley Bradshaw (Author), Narinder Singh (Author), Aaron Johnson (Author), Pippa Storey (Author), Hana Salati (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary drug delivery aims to deliver particles deep into the lungs, bypassing the mouth-throat airway geometry. However, micron particles under high flow rates are susceptible to inertial impaction on anatomical sites that serve as a defense system to filter and prevent foreign particles from ent...