Remote-controlled dexamethasone-duration on eye-surface with a micelle-magnetic nanoparticulate co-delivery system for dry eye disease

• Main Authors: Qinxiang Zheng (Author), Chaoxiang Ge (Author), Kexin Li (Author), Longxin Wang (Author), Xiaoyu Xia (Author), Xiao Liu (Author), Rashid Mehmood (Author), Jianliang Shen (Author), Kaihui Nan (Author), Wei Chen (Author), Sen Lin (Author)
• Format: Book
• Published: Elsevier, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dexamethasone (DEX) is used to treat ocular surface diseases. However, regulating DEX duration in tears while preventing its absorption into the anterior chamber is critical for balancing its therapy effects and the side effects. In this study, a novel magnetic nanoparticle (MNP)-micelle (MC) co-del...