Relationship between hypoxia and downstream pathogenic pathways in preeclampsia

• Autores principales: Henri Augusto Korkes (Autor), Leandro De Oliveira (Autor), Nelson Sass (Autor), Saira Salahuddin (Autor), S. Ananth Karumanchi (Autor), Augustine Rajakumar (Autor)
• Formato: Libro
• Publicado: Taylor & Francis Group, 2017-04-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Defects in angiogenesis and mitochondrial function in the placenta contribute to the pathogenesis of preeclampsia; however upstream regulators of these pathways are not known. It has been argued that placental hypoxia secondary to abnormal spiral artery remodeling may play a causal role in the angio...