Identification of Small Molecule Inhibitors of <i>Staphylococcus aureus</i> RnpA

• Glavni autori: Jennifer M. Colquhoun (Autor), Lisha Ha (Autor), Andrew Beckley (Autor), Brinkley Meyers (Autor), Daniel P. Flaherty (Autor), Paul M. Dunman (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2019-04-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

<i>Staphylococcus aureus</i> RnpA is thought to be a unique dual functional antimicrobial target that is required for two essential cellular processes, precursor tRNA processing and messenger RNA degradation. Herein, we used a previously described whole cell-based mupirocin synergy assay...