HO-1 Induction by CO-RM2 Attenuates TNF-α-Induced Cytosolic Phospholipase A2 Expression via Inhibition of PKCα-Dependent NADPH Oxidase/ROS and NF-κB

• Những tác giả chính: Pei-Ling Chi (Tác giả), Chun-Ju Liu (Tác giả), I-Ta Lee (Tác giả), Yu-Wen Chen (Tác giả), Li-Der Hsiao (Tác giả), Chuen-Mao Yang (Tác giả)
• Định dạng: Sách
• Được phát hành: Hindawi Limited, 2014-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Rheumatoid arthritis (RA) is characterized by chronic inflammatory infiltration of the synovium and elevation of proinflammatory cytokines. Cytosolic phospholipase A2 (cPLA2) is involved in the development of inflammatory diseases. Heme oxygenase-1 (HO-1) has been shown to possess anti-inflammatory...