Stimulation of airway and intestinal mucosal secretion by natural coumarin CFTR activators

• Main Authors: Hong eYang (Author), Lina eXu (Author), Yujie eSui (Author), Xin eLiu (Author), Chengyan eHe (Author), Rouyu eFang (Author), Jia eLiu (Author), Feng eHao (Author), Tong-Hui eMa (Author)
• Format: Book
• Published: Frontiers Media S.A., 2011-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mutations of cystic fibrosis transmembrane conductance regulator (CFTR) cause lethal hereditary disease cystic fibrosis (CF) that involves extensive destruction and dysfunction of serous epithelium. Possible pharmacological therapy includes correction of defective intracellular processing and abnorm...