Cofilin Inhibitor Improves Neurological and Cognitive Functions after Intracerebral Hemorrhage by Suppressing Endoplasmic Reticulum Stress Related-Neuroinflammation

• Hoofdauteurs: Daniyah A. Almarghalani (Auteur), Ghaith A. Bahader (Auteur), Mohammad Ali (Auteur), L. M. Viranga Tillekeratne (Auteur), Zahoor A. Shah (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2024-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Neuroinflammation after intracerebral hemorrhage (ICH) is a crucial factor that determines the extent of the injury. Cofilin is a cytoskeleton-associated protein that drives neuroinflammation and microglia activation. A novel cofilin inhibitor (CI) synthesized and developed in our lab has turned out...