A fast, miniaturised in-vitro assay developed for quantification of lipase enzyme activity

• Main Authors: Ariane Menden (Author), Davane Hall (Author), Daniel Paris (Author), Venkatarian Mathura (Author), Fiona Crawford (Author), Michael Mullan (Author), Stefan Crynen (Author), Ghania Ait-Ghezala (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The discovery of allosteric modulators is a multi-disciplinary approach, which is time- and cost-intensive. High-throughput screening combined with novel computational tools can reduce these factors. Thus, we developed an enzyme activity assay, which can be included in the drug discovery work-flow s...