Evaluation of Drug Blood-Brain-Barrier Permeability Using a Microfluidic Chip

• Main Authors: Jung Yoon Yang (Author), Dae-Seop Shin (Author), Moonkyu Jeong (Author), Seong Soon Kim (Author), Ha Neul Jeong (Author), Byung Hoi Lee (Author), Kyu-Seok Hwang (Author), Yuji Son (Author), Hyeon-Cheol Jeong (Author), Chi-Hoon Choi (Author), Kyeong-Ryoon Lee (Author), Myung Ae Bae (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The blood-brain-barrier (BBB) is made up of blood vessels whose permeability enables the passage of some compounds. A predictive model of BBB permeability is important in the early stages of drug development. The predicted BBB permeabilities of drugs have been confirmed using a variety of in vitro m...