Correlations between preclinical BJAB assay ranking of antisense drugs and clinical trial adverse events
Abstract This analysis sought to assess the clinical predictivity of an in vitro assay which utilized the human B‐lymphoma BJAB cell line, for identification of antisense oligonucleotides (ASOs) with the potential to elicit innate immune activation in humans. Adverse events (AEs) from clinical trial...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
Wiley,
2023-04-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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