Du Huo Ji Sheng Tang inhibits Notch1 signaling and subsequent NLRP3 activation to alleviate cartilage degradation in KOA mice

• Váldodahkkit: Wen-jin Chen (Dahkki), Yin Zhuang (Dahkki), Wei Peng (Dahkki), Wei Cui (Dahkki), Shu-jun Zhang (Dahkki), Jian-wei Wang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: BMC, 2023-06-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract Background Knee osteoarthritis (KOA) has a complex pathological mechanism and is difficult to cure. The traditional medicine Du Huo Ji Sheng Tang (DHJST) has been used for the treatment of KOA for more than one thousand years, but its mechanism for treating KOA has not been revealed. In our...