Snakebite drug discovery: high-throughput screening to identify novel snake venom metalloproteinase toxin inhibitors
Snakebite envenoming results in ∼100,000 deaths per year, with close to four times as many victims left with life-long sequelae. Current antivenom therapies have several limitations including high cost, variable cross-snake species efficacy and a requirement for intravenous administration in a clini...
Saved in:
Main Authors: | Rachel H. Clare (Author), Charlotte A. Dawson (Author), Adam Westhorpe (Author), Laura-Oana Albulescu (Author), Christopher M. Woodley (Author), Nada Mosallam (Author), Daniel J. W. Chong (Author), Jeroen Kool (Author), Neil G. Berry (Author), Paul M. O'Neill (Author), Nicholas R. Casewell (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2024-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Optimizing drug discovery for snakebite envenoming via a high-throughput phospholipase A2 screening platform
by: Laura-Oana Albulescu, et al.
Published: (2024) -
Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically diverse snake venoms.
by: Nessrin Alomran, et al.
Published: (2021) -
Neutralising effects of small molecule toxin inhibitors on nanofractionated coagulopathic Crotalinae snake venoms
by: Chunfang Xie, et al.
Published: (2020) -
Correction: Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically diverse snake venoms.
by: Nessrin Alomran, et al.
Published: (2022) -
Correction: Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically diverse snake venoms
by: Nessrin Alomran, et al.
Published: (2022)