Pharmacophore mapping: Prediction of BCR-ABL kinase inhibitory activity of α-benzylthio chalcones
In this investigation, 3D pharmacophore modeling studies were performed on a diverse set of 33 α-benzylthio chalcone derivatives that demonstrate anticancer activity by blocking BCR-ABL phosphorylation in leukemic cells. Pharmacophore modeling is based on the principle of the alignment of pharmacoph...
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| Format: | Livre |
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Faculty of Pharmacy, Cairo University,
2014-06-01T00:00:00Z.
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