Bioanalytical method development and validation for the simultaneous estimation of Olanzapine and Samidorphan in rabbit plasma by using HPLC-MS/MS and application to pharmacokinetic study

Abstract Background Samidorphan is an opioid antagonist while Olanzapine is an effective medication for schizophrenia and bipolar disorder. A unique and accurate MS/HPLC approach due to simultaneous measurement of Olanzapine and Samidorphan is, therefore, more urgently required. Simultaneous quantif...

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Main Authors: Rambabu Kantipudi (Author), Sugandha Kumar Pavuluri (Author)
Format: Book
Published: SpringerOpen, 2024-01-01T00:00:00Z.
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3rd Floor Main Library

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