Methanol extract of Dicranopteris linearis L. leaves impedes acetaminophen-induced liver intoxication partly by enhancing the endogenous antioxidant system

• Main Authors: Zainul Amiruddin Zakaria (Author), Farah Hidayah Kamisan (Author), Maizatul Hasyima Omar (Author), Nur Diyana Mahmood (Author), Fezah Othman (Author), Siti Selina Abdul Hamid (Author), Muhammad Nazrul Hakim Abdullah (Author)
• Format: Book
• Published: BMC, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The present study investigated the potential of methanolic extract of Dicranopteris linearis (MEDL) leaves to attenuate liver intoxication induced by acetaminophen (APAP) in rats. Methods A group of mice (n = 5) treated orally with a single dose (5000 mg/kg) of MEDL was first sub...