PAR2 controls cholesterol homeostasis and lipid metabolism in nonalcoholic fatty liver disease

• मुख्य लेखकों: Rajashree Rana (लेखक), Andrew M. Shearer (लेखक), Elizabeth K. Fletcher (लेखक), Nga Nguyen (लेखक), Srijoy Guha (लेखक), Daniel H. Cox (लेखक), Manal Abdelmalek (लेखक), Ying Wang (लेखक), James D. Baleja (लेखक), Lidija Covic (लेखक), Athan Kuliopulos (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2019-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objective: Increases in hepatic and plasma cholesterol occur in patients with nonalcoholic fatty liver disease (NAFLD), although the reason for this is not well understood. We investigated whether Protease-Activated Receptor 2 (PAR2) plays a role in cholesterol and lipid homeostasis in NAFLD. Method...