PAR2 controls cholesterol homeostasis and lipid metabolism in nonalcoholic fatty liver disease

• Main Authors: Rajashree Rana (Author), Andrew M. Shearer (Author), Elizabeth K. Fletcher (Author), Nga Nguyen (Author), Srijoy Guha (Author), Daniel H. Cox (Author), Manal Abdelmalek (Author), Ying Wang (Author), James D. Baleja (Author), Lidija Covic (Author), Athan Kuliopulos (Author)
• Format: Book
• Published: Elsevier, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Increases in hepatic and plasma cholesterol occur in patients with nonalcoholic fatty liver disease (NAFLD), although the reason for this is not well understood. We investigated whether Protease-Activated Receptor 2 (PAR2) plays a role in cholesterol and lipid homeostasis in NAFLD. Method...