Hesperidin Protects SH−SY5Y Neuronal Cells against High Glucose−Induced Apoptosis via Regulation of MAPK Signaling

• Main Authors: Chaemoon Lim (Author), Ao Xuan Zhen (Author), Sungwoo Ok (Author), Pincha Devage Sameera Madushan Fernando (Author), Herath Mudiyanselage Udari Lakmini Herath (Author), Mei Jing Piao (Author), Kyoung Ah Kang (Author), Jin Won Hyun (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neurodegenerative diseases are associated with neuronal cell death through apoptosis. Apoptosis is tightly associated with the overproduction of reactive oxygen species (ROS), and high glucose levels contribute to higher oxidative stress in diabetic patients. Hesperidin, a natural active compound, h...