Intraoral Drug Delivery: Highly Thiolated κ-Carrageenan as Mucoadhesive Excipient

• Ngā kaituhi matua: Gergely Kali (Author), Andrea Fürst (Author), Nuri Ari Efiana (Author), Aida Dizdarević (Author), Andreas Bernkop-Schnürch (Author)
• Hōputu: Pukapuka
• I whakaputaina: MDPI AG, 2023-07-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Aim: This study aims to design a novel thiolated κ-carrageenan (κ-CA-SH) and evaluate its potential as an excipient for the design of mucoadhesive drug delivery systems. Methods: Native κ-carrageenan (κ-CA) was thiolated with phosphorous pentasulfide in sulfolane and characterized via <sup>1&l...