Molecular Pharmacology of P2X Receptors: Exploring Druggable Domains Revealed by Structural Biology

Molecular Pharmacology of P2X Receptors: Exploring Druggable Domains Revealed by Structural Biology

Extracellular ATP is a critical signaling molecule that is found in a wide range of concentrations across cellular environments. The family of nonselective cation channels that sense extracellular ATP, termed P2X receptors (P2XRs), is composed of seven subtypes (P2X1-P2X7) that assemble as functiona...

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Bibliographic Details
Main Authors: Adam C. Oken (Author), Ipsita Krishnamurthy (Author), Jonathan C. Savage (Author), Nicolas E. Lisi (Author), Michael H. Godsey (Author), Steven E. Mansoor (Author)
Format: Book
Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
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