Molecular Pharmacology of P2X Receptors: Exploring Druggable Domains Revealed by Structural Biology

• 主要な著者: Adam C. Oken (著者), Ipsita Krishnamurthy (著者), Jonathan C. Savage (著者), Nicolas E. Lisi (著者), Michael H. Godsey (著者), Steven E. Mansoor (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Extracellular ATP is a critical signaling molecule that is found in a wide range of concentrations across cellular environments. The family of nonselective cation channels that sense extracellular ATP, termed P2X receptors (P2XRs), is composed of seven subtypes (P2X1-P2X7) that assemble as functiona...