Inhibition of Autophagy Enhances Sunitinib-Induced Cytotoxicity in Rat Pheochromocytoma PC12 cells

• Автори: Tatsuhiko Ikeda (Автор), Kiyo-aki Ishii (Автор), Yuria Saito (Автор), Masahiro Miura (Автор), Aoi Otagiri (Автор), Yasushi Kawakami (Автор), Hitoshi Shimano (Автор), Hisato Hara (Автор), Kazuhiro Takekoshi (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2013-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Sunitinib is an oral multitargeted receptor tyrosine kinase inhibitor with antiangiogenic and antitumor activity that mainly targets vascular endothelial growth factor receptors, and recently, it has been shown to be an active agent for the treatment of malignant pheochromocytomas. Previously, we de...