The utilization of advance telemetry to investigate critical physiological parameters including electroencephalography in cynomolgus macaques following aerosol challenge with eastern equine encephalitis virus.

• Main Authors: John C Trefry (Author), Franco D Rossi (Author), Michael V Accardi (Author), Brandi L Dorsey (Author), Thomas R Sprague (Author), Suzanne E Wollen-Roberts (Author), Joshua D Shamblin (Author), Adrienne E Kimmel (Author), Pamela J Glass (Author), Lynn J Miller (Author), Crystal W Burke (Author), Anthony P Cardile (Author), Darci R Smith (Author), Sina Bavari (Author), Simon Authier (Author), William D Pratt (Author), Margaret L Pitt (Author), Farooq Nasar (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Most alphaviruses are mosquito-borne and can cause severe disease in humans and domesticated animals. In North America, eastern equine encephalitis virus (EEEV) is an important human pathogen with case fatality rates of 30-90%. Currently, there are no therapeutics or vaccines to treat and/or prevent...