Exploring novel MYH7 gene variants using in silico analyses in Korean patients with cardiomyopathy

• Hoofdauteurs: Oc-Hee Kim (Auteur), Jihyun Kim (Auteur), Youngjun Kim (Auteur), Soyoung Lee (Auteur), Beom Hee Lee (Auteur), Bong-Jo Kim (Auteur), Hyun-Young Park (Auteur), Mi-Hyun Park (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2024-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background Pathogenic variants of MYH7, which encodes the beta-myosin heavy chain protein, are major causes of dilated and hypertrophic cardiomyopathy. Methods In this study, we used whole-genome sequencing data to identify MYH7 variants in 397 patients with various cardiomyopathy subtypes...