Exploring novel MYH7 gene variants using in silico analyses in Korean patients with cardiomyopathy

• Main Authors: Oc-Hee Kim (Author), Jihyun Kim (Author), Youngjun Kim (Author), Soyoung Lee (Author), Beom Hee Lee (Author), Bong-Jo Kim (Author), Hyun-Young Park (Author), Mi-Hyun Park (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Pathogenic variants of MYH7, which encodes the beta-myosin heavy chain protein, are major causes of dilated and hypertrophic cardiomyopathy. Methods In this study, we used whole-genome sequencing data to identify MYH7 variants in 397 patients with various cardiomyopathy subtypes...