Facile synthesis, spectral characterization, antimicrobial and in vitro cytotoxicity of novel N3,N5-diisonicotinyl-2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarbohydrazide derivatives

• Main Authors: Karthikeyan Elumalai (Author), Manogaran Elumalai (Author), Kalpana Eluri (Author), Sivaneswari Srinivasan (Author), Mohamed Ashraf Ali (Author), Basu Venkateswara Reddy (Author), Sarada Prasad Sarangi (Author)
• Format: Book
• Published: Faculty of Pharmacy, Cairo University, 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A new series of some novel isoniazid condensed 1,4-dihydropyridines was prepared by reaction of N-(3-oxobutanoyl) isonicotinohydrazide with aryl aldehyde and 25-30% ammonia solution in the presence of catalytic amount of barium nitrate as an efficient catalyst. The confirmation of the chemical struc...