Peptides vs. Polymers: Searching for the Most Efficient Delivery System for Mitochondrial Gene Therapy

• Main Authors: Rúben Faria (Author), Milan Paul (Author), Swati Biswas (Author), Eric Vivès (Author), Prisca Boisguérin (Author), Ângela Sousa (Author), Diana Costa (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2022-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Together with the nucleus, the mitochondrion has its own genome. Mutations in mitochondrial DNA are responsible for a variety of disorders, including neurodegenerative diseases and cancer. Current therapeutic approaches are not effective. In this sense, mitochondrial gene therapy emerges as a valuab...