Elevated ZNF704 expression is associated with poor prognosis of uveal melanoma and promotes cancer cell growth by regulating AKT/mTOR signaling

• Hlavní autoři: Jingting Luo (Autor), Haowen Li (Autor), Jingying Xiu (Autor), Jingyao Zeng (Autor), Zhaoxun Feng (Autor), Hanqing Zhao (Autor), Yang Li (Autor), Wenbin Wei (Autor)
• Médium: Kniha
• Vydáno: BMC, 2023-04-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Abstract Background Uveal melanoma (UM) is the most common intraocular malignancy in adults, with a poor survival prognosis. To date, limited understanding of UM's molecular mechanisms constitutes an obstacle to developing effective therapy. In this study, we examined key regulators mediating U...