Comprehensive PBPK model to predict drug interaction potential of Zanubrutinib as a victim or perpetrator

Abstract A physiologically based pharmacokinetic (PBPK) model was developed to evaluate and predict (1) the effect of concomitant cytochrome P450 3A (CYP3A) inhibitors or inducers on the exposures of zanubrutinib, (2) the effect of zanubrutinib on the exposures of CYP3A4, CYP2C8, and CYP2B6 substrat...

Full description

Saved in:
Bibliographic Details
Main Authors: Kun Wang (Author), Xueting Yao (Author), Miao Zhang (Author), Dongyang Liu (Author), Yuying Gao (Author), Srikumar Sahasranaman (Author), Ying C. Ou (Author)
Format: Book
Published: Wiley, 2021-05-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available