Porphyromonas gingivalis infection promotes mitochondrial dysfunction through Drp1-dependent mitochondrial fission in endothelial cells

• Main Authors: Tong Xu (Author), Qin Dong (Author), Yuxiao Luo (Author), Yanqing Liu (Author), Liang Gao (Author), Yaping Pan (Author), Dongmei Zhang (Author)
• Format: Book
• Published: Nature Publishing Group, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Porphyromonas gingivalis (P. gingivalis), a key pathogen in periodontitis, has been shown to accelerate the progression of atherosclerosis (AS). However, the definite mechanisms remain elusive. Emerging evidence supports an association between mitochondrial dysfunction and AS. In our study,...