Loss of p21-activated kinase Mbt/PAK4 causes Parkinson-like phenotypes in Drosophila

• Prif Awduron: Stephanie M. Pütz (Awdur), Jette Kram (Awdur), Elisa Rauh (Awdur), Sophie Kaiser (Awdur), Romy Toews (Awdur), Yi Lueningschroer-Wang (Awdur), Dirk Rieger (Awdur), Thomas Raabe (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: The Company of Biologists, 2021-06-01T00:00:00Z.
• Pynciau: article
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Parkinson's disease (PD) provokes bradykinesia, resting tremor, rigidity and postural instability, and also non-motor symptoms such as depression, anxiety, sleep and cognitive impairments. Similar phenotypes can be induced in Drosophila melanogaster through modification of PD-relevant genes or...