Analogous β-Carboline Alkaloids Harmaline and Harmine Ameliorate Scopolamine-Induced Cognition Dysfunction by Attenuating Acetylcholinesterase Activity, Oxidative Stress, and Inflammation in Mice

• Egile Nagusiak: Shu-Ping Li (Egilea), Yu-Wen Wang (Egilea), Sheng-Lan Qi (Egilea), Yun-Peng Zhang (Egilea), Gang Deng (Egilea), Wen-Zheng Ding (Egilea), Chao Ma (Egilea), Qi-Yan Lin (Egilea), Hui-Da Guan (Egilea), Wei Liu (Egilea), Xue-Mei Cheng (Egilea), Chang-Hong Wang (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The analogous β-carboline alkaloids, harmaline (HAL) and harmine (HAR), possess a variety of biological properties, including acetylcholinesterase (AChE) inhibitory activity, antioxidant, anti-inflammatory, and many others, and have great potential for treating Alzheimer's disease (AD). However...