Systematic Review and Meta-Analysis of the Effect of Loop Diuretics on Antibiotic Pharmacokinetics

• Main Authors: David A. Kerling (Author), Sarah C. Clarke (Author), Jesse P. DeLuca (Author), Martin O. Evans (Author), Adrian T. Kress (Author), Robert J. Nadeau (Author), Daniel J. Selig (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Loop diuretics and antibiotics are commonly co-prescribed across many clinical care settings. Loop diuretics may alter antibiotic pharmacokinetics (PK) via several potential drug interactions. A systematic review of the literature was performed to investigate the impact of loop diuretics on antibiot...