Vitamin E TPGS-Poloxamer Nanoparticles Entrapping a Novel PI3Kα Inhibitor Potentiate Its Activity against Breast Cancer Cell Lines

N-(2-fluorphenyl)-6-chloro-4-hydroxy-2-quinolone-3-carboxamide (R19) is a newly synthesized phosphatidylinositol 3-kinase alpha (PI3Kα) inhibitor with promising activity against cancer cells. The purpose of this study was to develop a polymeric nanoparticle (NP) formulation for R19 to address its po...

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Main Authors: Suhair Sunoqrot (Author), Sundos Aliyeh (Author), Samah Abusulieh (Author), Dima Sabbah (Author)
Format: Book
Published: MDPI AG, 2022-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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