Elevated IgM levels as a marker for a unique phenotype in patients with Ataxia telangiectasia

• Main Authors: Alexander Krauthammer (Author), Avishay Lahad (Author), Lior Goldberg (Author), Ifat Sarouk (Author), Batia Weiss (Author), Raz Somech (Author), Michalle Soudack (Author), Itai M. Pessach (Author)
• Format: Book
• Published: BMC, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Ataxia telangiectasia (AT) is a rare, multi-systemic, genetic disorder. Mutations in the ATM gene cause dysfunction in cell-cycle, apoptosis and V (D) J recombination leading to neurodegeneration, cellular, humoral immunodeficiencies and predisposition to malignancies. Previous s...