Prunetin in a GPR30-dependent manner mitigates renal ischemia/reperfusion injury in rats via interrupting indoxyl sulfate/TLR4/TRIF, RIPK1/RIPK3/MLKL, and RIPK3/PGAM5/DRP-1 crosstalk

The potential health benefits of phytochemicals in preventing and treating diseases have gained increasing attention. Here, we proved that the methylated isoflavone prunetin possesses a reno-therapeutic effect against renal ischemia/reperfusion (I/R) insult by activating G protein-coupled receptor 3...

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Main Authors: Ahmed B. Hamed (Author), Hanan S. El-Abhar (Author), Dalaal M. Abdallah (Author), Kawkab A. Ahmed (Author), Yasmin S. Abulfadl (Author)
Format: Book
Published: Elsevier, 2023-11-01T00:00:00Z.
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