Anti-angiogenic effects of valproic acid in a mouse model of oxygen-induced retinopathy

Anti-angiogenic effects of valproic acid in a mouse model of oxygen-induced retinopathy

Pathological retinal angiogenesis contributes to the pathogenesis of several ocular diseases. Valproic acid, a widely used antiepileptic drug, exerts anti-angiogenic effects by inhibiting histone deacetylase (HDAC). Herein, we investigated the effects of valproic acid and vorinostat, a HDAC inhibito...

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Main Authors: Naoto Iizuka (Author), Akane Morita (Author), Chihiro Kawano (Author), Asami Mori (Author), Kenji Sakamoto (Author), Masakazu Kuroyama (Author), Kunio Ishii (Author), Tsutomu Nakahara (Author)
Format: Book
Published: Elsevier, 2018-11-01T00:00:00Z.
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3rd Floor Main Library

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