MAPK Cascade Signaling Is Involved in α-MMC Induced Growth Inhibition of Multiple Myeloma MM.1S Cells via G2 Arrest and Mitochondrial-Pathway-Dependent Apoptosis In Vitro

• Main Authors: Zi-Wei Cai (Author), Ting Ye (Author), Pei-Wen Jiang (Author), Yu-Jiao Liao (Author), Lin Wang (Author), Qing-Liang Zhang (Author), Wen-Qian Du (Author), Min Huang (Author), Ping Yang (Author), Min-Hui Li (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multiple myeloma is a hematological malignancy characterized by the unrestricted proliferation of plasma cells that secrete monoclonal immunoglobulins in the bone marrow. Alpha-momorcharin (α-MMC) is a type I ribosome-inactivating protein extracted from the seeds of the edible plant <i>Momordi...