Virus identification in unknown tropical febrile illness cases using deep sequencing.

• Main Authors: Nathan L Yozwiak (Author), Peter Skewes-Cox (Author), Mark D Stenglein (Author), Angel Balmaseda (Author), Eva Harris (Author), Joseph L DeRisi (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue virus is an emerging infectious agent that infects an estimated 50-100 million people annually worldwide, yet current diagnostic practices cannot detect an etiologic pathogen in ∼40% of dengue-like illnesses. Metagenomic approaches to pathogen detection, such as viral microarrays and deep seq...