A neutrophil-biomimic platform for eradicating metastatic breast cancer stem-like cells by redox microenvironment modulation and hypoxia-triggered differentiation therapy

• Main Authors: Yongchao Chu (Author), Yifan Luo (Author), Boyu Su (Author), Chao Li (Author), Qin Guo (Author), Yiwen Zhang (Author), Peixin Liu (Author), Hongyi Chen (Author), Zhenhao Zhao (Author), Zheng Zhou (Author), Yu Wang (Author), Chen Jiang (Author), Tao Sun (Author)
• Format: Book
• Published: Elsevier, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metastasis accounts for 90% of breast cancer deaths, where the lethality could be attributed to the poor drug accumulation at the metastatic loci. The tolerance to chemotherapy induced by breast cancer stem cells (BCSCs) and their particular redox microenvironment further aggravate the therapeutic d...