Lyso-DGTS Lipid Derivatives Enhance PON1 Activities and Prevent Oxidation of LDL: A Structure-Activity Relationship Study

• Main Authors: Ali Khattib (Author), Sanaa Musa (Author), Majdi Halabi (Author), Tony Hayek (Author), Soliman Khatib (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2022-10-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Paraoxonase 1 (PON1) plays a role in regulating reverse cholesterol transport and has antioxidative, anti-inflammatory, antiapoptotic, vasodilative, and antithrombotic activities. Scientists are currently focused on the modulation of PON1 expression using different pharmacological, nutritional, and...