Extracellular Cardiolipin Modulates Select Immune Functions of Astrocytes in Toll-Like Receptor (TLR) 4-Dependent Manner

• Main Authors: Taryn E. Murray (Author), Tyler J. Wenzel (Author), Svetlana Simtchouk (Author), Bridget K. Greuel (Author), Julien Gibon (Author), Andis Klegeris (Author)
• 格式: 图书
• 出版: Hindawi Limited, 2022-01-01T00:00:00Z.
• 主题: article
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Alzheimer's disease (AD) is characterized by chronic neuroinflammation, which is partially mediated by dysregulated functions of glial cells. Cardiolipin (CL) is a phospholipid normally confined to the inner mitochondrial membrane; however, it has been detected in human sera, indicating that it...