Analytical Performance Evaluation of New DESI Enhancements for Targeted Drug Quantification in Tissue Sections

• Main Authors: Margaux Fresnais (Author), Siwen Liang (Author), Marius Breitkopf (Author), Joshua Raoul Lindner (Author), Emmanuelle Claude (Author), Steven Pringle (Author), Pavel A. Levkin (Author), Konstantin Demir (Author), Julia Benzel (Author), Julia Sundheimer (Author), Britta Statz (Author), Kristian W. Pajtler (Author), Stefan M. Pfister (Author), Walter E. Haefeli (Author), Jürgen Burhenne (Author), Rémi Longuespée (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Desorption/ionization (DI)-mass spectrometric (MS) methods offer considerable advantages of rapidity and low-sample input for the analysis of solid biological matrices such as tissue sections. The concept of desorption electrospray ionization (DESI) offers the possibility to ionize compounds from so...