Intrathecal Methotrexate-Induced Necrotizing Myelopathy: A Case Report and Review of Histologic Features
Central nervous system (CNS) relapse of acute lymphoblastic leukemia (ALL) is associated with a poor prognosis. However, prophylactic measures, including intrathecal (IT) methotrexate, reduce the incidence of CNS relapse in these patients considerably. Unfortunately, IT methotrexate can cause severa...
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SAGE Publishing,
2018-11-01T00:00:00Z.
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