Synthesis, molecular modelling and anticancer evaluation of new pyrrolo[1,2-b]pyridazine and pyrrolo[2,1-a]phthalazine derivatives

• المؤلفون الرئيسيون: Lacramioara Popovici (مؤلف), Roxana-Maria Amarandi (مؤلف), Ionel I. Mangalagiu (مؤلف), Violeta Mangalagiu (مؤلف), Ramona Danac (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Two new series of heterocyclic derivatives with potential anticancer activity, in which a pyrrolo[1,2-b]pyridazine or a pyrrolo[2,1-a]phthalazine moiety was introduced in place of the 3'-hydroxy-4'-methoxyphenyl ring of phenstatin have been synthesised and their structure-activity relation...