Synergetic Impact of Combined 5-Fluorouracil and Rutin on Apoptosis in PC3 Cancer Cells through the Modulation of P53 Gene Expression

• Main Authors: Atefeh Satari (Author), Sayed Asadollah Amini (Author), Elham Raeisi (Author), Yves Lemoigne (Author), Esfandiar Heidarian (Author)
• 格式: 圖書
• 出版: Tabriz University of Medical Sciences, 2019-08-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Purpose: Prostate cancer is as far the most prevalent male cancer. Rutin (a glycoside from quercetin flavonoid) displays antioxidant activity leading to cell apoptosis. Combined effects of rutin with the widely used anti-cancer drug, 5-fluorouracil (5-FU), on prostate cancer cell line (PC3) was inve...