Comparison of central versus peripheral delivery of pregabalin in neuropathic pain states

• Main Authors: Martinez Jose A (Author), Kasamatsu Manami (Author), Rosales-Hernandez Alma (Author), Hanson Leah R (Author), Frey William H (Author), Toth Cory C (Author)
• Format: Book
• Published: SAGE Publishing, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Although pregabalin therapy is beneficial for neuropathic pain (NeP) by targeting the CaVα₂δ-1 subunit, its site of action is uncertain. Direct targeting of the central nervous system may be beneficial for the...