14-3-3 Protein Protects Against Cardiac Endoplasmic Reticulum Stress (ERS) and ERS-Initiated Apoptosis in Experimental Diabetes

• Main Authors: Flori R. Sari (Author), Kenichi Watanabe (Author), Rajarajan A. Thandavarayan (Author), Meilei Harima (Author), Shaosong Zhang (Author), Anthony J. Muslin (Author), Makoto Kodama (Author), Yoshifusa Aizawa (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetic cardiomyopathy and nephropathy induce endoplasmic reticulum stress (ERS) and ERS-initiated apoptosis. The primary function of 14-3-3 protein is to inhibit apoptosis, but the roles of this protein in protecting against cardiac ERS and apoptosis in the diabetic heart are largely unknown. In t...